Discovery and characterisation of novel anticancer compounds acting on sphingosine kinase
There is a critical need to develop novel anticancer therapeutics. Accumulating evidence has demonstrated that sphingosine kinase (SK) is a promising target for the treatment of cancer. There are two SK isoforms, termed SK1 and SK2. SK phosphorylates sphingosine to form sphingosine-1-phosphate which...
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University of Strathclyde
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618851 |