ADAMTS13 polymorphisms : role in predicting renal and cardiovascular events in type 2 diabetes and response to therapy

ADAMTS13 polymorphisms : role in predicting renal and cardiovascular events in type 2 diabetes and response to therapy

In diabetics, impaired ADAMTS13 proteolysis of highly-thrombogenic VWF multimers may accelerate renal and cardiovascular complications, that are major causes of illness and death in these patients. Restoring physiological VWF handling might contribute to ACE inhibitors (ACEi) reno- and cardioprotect...

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Bibliographic Details
Main Author:	Rurali, Erica
Published:	Open University 2013
Subjects:	616.4624
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607475

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