ADAMTS13 polymorphisms : role in predicting renal and cardiovascular events in type 2 diabetes and response to therapy
In diabetics, impaired ADAMTS13 proteolysis of highly-thrombogenic VWF multimers may accelerate renal and cardiovascular complications, that are major causes of illness and death in these patients. Restoring physiological VWF handling might contribute to ACE inhibitors (ACEi) reno- and cardioprotect...
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Open University
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607475 |