Production of high value drug metabolites using engineered cytochromes P450

Production of drug metabolites is an area of biotechnology where manufacture bycytochromes P450 (P450s) offers significant advantages over synthetic methods. P450 BM3from Bacillus megaterium is an ideal candidate for metabolite synthesis. It is a soluble fusionof a P450 to its partner (cytochrome P4...

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Bibliographic Details
Main Author: Butler, Christopher
Other Authors: Munro, Andrew; Leys, David
Published: University of Manchester 2013
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607118