Comparative analysis of protein quality control systems in two mouse models of familial amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous disease with considerable variability in the disease course even in familial cases associated with autosomal dominant SOD1 gene mutations. Previously, we have shown that SOD1G93A mice, the most widely used model of ALS, exhibit remark...

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Bibliographic Details
Main Author: Marino, Marianna
Published: Open University 2013
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.606837

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