Design and synthesis of solid-supported reagents and their use in multi-step synthesis
Solid-supported reagents are being developed as a complementary technique to solid-phase organic synthesis. They offer the advantages of conducting clean chemistry with rapid purification of products and ease of reaction monitoring. This thesis describes the development of a solid-support bisdihydro...
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University of Cambridge
2002
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ndltd-bl.uk-oai-ethos.bl.uk-6049892017-12-24T16:17:57ZDesign and synthesis of solid-supported reagents and their use in multi-step synthesisJackson, Philip Stephen2002Solid-supported reagents are being developed as a complementary technique to solid-phase organic synthesis. They offer the advantages of conducting clean chemistry with rapid purification of products and ease of reaction monitoring. This thesis describes the development of a solid-support bisdihydropyran and its use in the resolution of diols and the use of solid-supported reagents in the multi-step synthesis of epothilone B. Also covered is work towards tagged chiral induction reagents for solution-phase reactions with solid phase scavenger purification.547University of Cambridgehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604989https://www.repository.cam.ac.uk/handle/1810/251819Electronic Thesis or Dissertation |
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547 |
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547 Jackson, Philip Stephen Design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| description |
Solid-supported reagents are being developed as a complementary technique to solid-phase organic synthesis. They offer the advantages of conducting clean chemistry with rapid purification of products and ease of reaction monitoring. This thesis describes the development of a solid-support bisdihydropyran and its use in the resolution of diols and the use of solid-supported reagents in the multi-step synthesis of epothilone B. Also covered is work towards tagged chiral induction reagents for solution-phase reactions with solid phase scavenger purification. |
| author |
Jackson, Philip Stephen |
| author_facet |
Jackson, Philip Stephen |
| author_sort |
Jackson, Philip Stephen |
| title |
Design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| title_short |
Design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| title_full |
Design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| title_fullStr |
Design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| title_full_unstemmed |
Design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| title_sort |
design and synthesis of solid-supported reagents and their use in multi-step synthesis |
| publisher |
University of Cambridge |
| publishDate |
2002 |
| url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604989 |
| work_keys_str_mv |
AT jacksonphilipstephen designandsynthesisofsolidsupportedreagentsandtheiruseinmultistepsynthesis |
| _version_ |
1718575702541860864 |