Studies on genomic G-quadruplexes

In this dissertation, I focus on a four-stranded structure that can be formed by guanine-rich sequences. These are known as G-quadruplexes or G-tetrads. I begin by investigating the structural properties of this structure, and how sensitive it is to mutations and deletions. I then consider the struc...

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Bibliographic Details
Main Author: Huppert, J. L.
Published: University of Cambridge 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604822