Characterisation of the human Arl4 and Arl8 families of small GTPases

Two closely related human Arls, Arl8a and Arl8b, were found to localise to lysosomes in mammalian cells. conventionally, membrane binding of Arf and Arl proteins is mediated by both an N-terminal myristoyl group and an N-terminal amphipathic helix that are inserted into the lipid bilayer upon activa...

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Bibliographic Details
Main Author: Hofmann, Irmgard Maria Rita
Published: University of Cambridge 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604140