Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C

This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substituti...

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Main Author: Hewitt, P. R.
Published: University of Cambridge 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603980
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spelling ndltd-bl.uk-oai-ethos.bl.uk-6039802015-03-20T06:04:30ZStudies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine CHewitt, P. R.2006This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substitution pattern. The third chapter describes further development of the methodology described in the second chapter and its application in the total synthesis of okaramine C. The fourth chapter describes synthetic efforts towards the total synthesis of CJ-12663, utilising the methodology described in the second chapter.547.7University of Cambridgehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603980Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 547.7
spellingShingle 547.7
Hewitt, P. R.
Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
description This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substitution pattern. The third chapter describes further development of the methodology described in the second chapter and its application in the total synthesis of okaramine C. The fourth chapter describes synthetic efforts towards the total synthesis of CJ-12663, utilising the methodology described in the second chapter.
author Hewitt, P. R.
author_facet Hewitt, P. R.
author_sort Hewitt, P. R.
title Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
title_short Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
title_full Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
title_fullStr Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
title_full_unstemmed Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
title_sort studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine c
publisher University of Cambridge
publishDate 2006
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603980
work_keys_str_mv AT hewittpr studiesinthesynthesisofpyrroloindolealkaloidsandthetotalsynthesisofokaraminec
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