Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substituti...
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ndltd-bl.uk-oai-ethos.bl.uk-6039802015-03-20T06:04:30ZStudies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine CHewitt, P. R.2006This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substitution pattern. The third chapter describes further development of the methodology described in the second chapter and its application in the total synthesis of okaramine C. The fourth chapter describes synthetic efforts towards the total synthesis of CJ-12663, utilising the methodology described in the second chapter.547.7University of Cambridgehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603980Electronic Thesis or Dissertation |
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547.7 Hewitt, P. R. Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C |
description |
This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substitution pattern. The third chapter describes further development of the methodology described in the second chapter and its application in the total synthesis of okaramine C. The fourth chapter describes synthetic efforts towards the total synthesis of CJ-12663, utilising the methodology described in the second chapter. |
author |
Hewitt, P. R. |
author_facet |
Hewitt, P. R. |
author_sort |
Hewitt, P. R. |
title |
Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C |
title_short |
Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C |
title_full |
Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C |
title_fullStr |
Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C |
title_full_unstemmed |
Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C |
title_sort |
studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine c |
publisher |
University of Cambridge |
publishDate |
2006 |
url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603980 |
work_keys_str_mv |
AT hewittpr studiesinthesynthesisofpyrroloindolealkaloidsandthetotalsynthesisofokaraminec |
_version_ |
1716795715385032704 |