Towards G-quadruplex recognition by porphyrins and porphyrazines

This thesis describes the development and synthesis of porphyrins and porphyrazines, with the potential to bind selectively to G-quadruplex DNA. The original idea was to generate Dynamic Combinatorial Libraries composed of porphyrinic building blocks equipped with thiol groups. Unfortunately, the ma...

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Bibliographic Details
Main Author: Goncalves, D. P. N.
Published: University of Cambridge 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599484