Regulation of the thiazide-sensitive sodium chloride transporter, NCCT
The thiazide-sensitive sodium chloride transporter, NCCT is found in the distal convoluted tubule. Reduced NCCT activity caused by thiazide diuretics or Gitelman syndrome leads to salt wasting and reduced blood pressure. Conversely, excessive NCCT activity seen in Gordon syndrome, due to mutations i...
| Main Author: | |
|---|---|
| Published: |
University of Cambridge
2010
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599443 |