Studies towards the synthesis of the spongistatins and remote asymmetric induction in aldol reactions

Spongistatin 1/ altohyrtin A (1) is a member of a family of naturally occurring marine derived macrolide natural products. These natural products possess potent cytotoxicity. All the spongistatins possess a highly complex 42-membered macrolide ring comprised of two spiroacetal systems, a hemi-acetal...

Full description

Bibliographic Details
Main Author: Gibson, K.
Published: University of Cambridge 1998
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599398