The role of molecular chaperones in the processing of wild-type and DeltaF508 CFTR
Cystic fibrosis (CF) is one of the most common autosomal recessive disorders affecting Caucasian populations. Seventy percent of CF alleles produce the protein ΔF508 CFTR, in which a single phenylalanine residue is missing from position 508 of the polypeptide chain. This is a processing mutant: ΔF50...
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University of Cambridge
1999
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599263 |