Proteolytic processing of proTGF-β1

Transforming growth factor beta 1 (TGF-β1) is translated as a proprotein. The main enzyme responsible for the proteolytic processing of proTGF-β1 is furin. The aim of this thesis is to characterise the proteolytic processing of proTGF-β1 and investigate whether this step may represent an important p...

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Bibliographic Details
Main Author: Bourne, G. L.
Published: University of Cambridge 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596808