The molecular function of the Drosophila PAR-1 kinase in establishing cell polarity

Through a structure-function analysis, I demonstrated the requirement of kinase activity for <i>Drosophila </i>PAR-1 function. Mammalian PAR-1 homologues, the MARKs, phosphorylate microtubule-associated proteins of the tau family to inhibit their interaction with microtubules. This bioch...

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Bibliographic Details
Main Author: Benton, R.
Published: University of Cambridge 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596581