Generation of recombinant factor H proteins to control alternative pathway activation in the kidney
The alternative pathway (AP) of complement activation is implicated in several renal pathologies. These include membranoproliferative glomerulonephritis (MPGN) type II and atypical haemolytic uraemic syndrome (aHUS). Factor H (FH), comprised of 20 short consensus repeats (SCRs), is the primary regul...
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University of Newcastle upon Tyne
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594505 |