An investigation into the pharmacology and regulation of the M1, M3 and M4 muscarinic acetylcholine receptors

Functional selectivity, which highlights the ability of ligands to differentially activate the signalling pathways linked to G protein-couple receptors (GPCRs) has provided an avenue for developing ligands with greater safety profiles. Pilocarpine (Pilo), a non-selective muscarinic acetylcholine rec...

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Bibliographic Details
Main Author: Prihandoko, Rudi
Other Authors: Tobin, Andrew
Published: University of Leicester 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593734