Design, synthesis and biological evaluation of new bacterial RNAP inhibitors

Bacterial resistance to antibiotics has been well documented since the emergence of resistance to the beta-lactams during the 1930s. The World Health Organisation considers it to be one of the three greatest threats to human health. Since the late 1980s, the pharmaceutical industry has relied upon t...

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Bibliographic Details
Main Author: McPhillie, Martin John
Published: University of Leeds 2012
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590309

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