An investigation into the use of 3D microscopy for the study of radiation-induced chromosome aberrations and nuclear architecture

Cellular exposure to ionising radiation (IR) generates chromosome aberrations (CA) that in turn lead to gene mutation and cell death. Although radiation-induced CA are known to result from the misrepair or lack of repair of DNA damage, the exact details of the conversion of such damage to CA remains...

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Bibliographic Details
Main Author: Thenet, Delphine
Other Authors: Peacock, John ; Jones, Lucy ; Wertheim, David
Published: Kingston University 2012
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.587378