Development of a topical formulation for the treatment of basal cell carcinoma
Despite the ability to modulate SHH signalling, EGF pathway inhibitors targeting pAKT and pERK may not be useful for treating basal cell carcinoma. Alternative SHH signalling inhibitors such as those that target the formation of the primary cilium may be highly effective.
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Cardiff University
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.585261 |
| Summary: | Despite the ability to modulate SHH signalling, EGF pathway inhibitors targeting pAKT and pERK may not be useful for treating basal cell carcinoma. Alternative SHH signalling inhibitors such as those that target the formation of the primary cilium may be highly effective. |
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