Development of an ex-vivo co-culture system to model pulpal infection by Streptococcus anginosus group bacteria
A reproducible model of infection of dental tissues by SAG bacteria has been produced which shows attachment patterns of bacteria and the effect on host tissues. This model can be used to further investigate processes involved in endodontic infections, including expression of virulence factors by ba...
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Cardiff University
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.585058 |
| Summary: | A reproducible model of infection of dental tissues by SAG bacteria has been produced which shows attachment patterns of bacteria and the effect on host tissues. This model can be used to further investigate processes involved in endodontic infections, including expression of virulence factors by bacteria and host response from the dental tissues. It may also be used in the future for testing novel antimicrobials for use in treating pulpal disease. |
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