Investigating the mechanisms of pathogenesis underlying inherited colorectal adenomatous polyposis
In order to investigate the role of nonsynonymous variants of the APC gene in inherited predisposition to colorectal adenomas (CRAs) the entire APC ORF was sequenced in 691 unrelated North American patients with CRAs and 969 healthy controls. There was significant over representation of rare inherit...
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Cardiff University
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584719 |