Modulation of CD4+ T cell responses by CD59a

CD59 is a GPI-anchored protein found in membrane microdomains known as lipid rafts. It is a complement regulator protein, which blocks the formation of the membrane attack complex by inhibiting binding of C9 to the C5-8 complex. Human CD59 has also been described as a co-stimulator of T cell activat...

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Bibliographic Details
Main Author: Longhi, Maria Paula
Published: Cardiff University 2006
Subjects:
615
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583895