Design and synthesis of inhibitors of critical target proteins implicated in cellular proliferation
Cyclin-Dependent Kinases (CDKs) are a family of protein kinases that control progression through the eukaryotic cell cycle. CDKs become activated when they form a complex with the appropriate cyclin protein, and are fully activated by phosphorylation. CDK inhibitors regulate the activity of CDK/cycl...
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Cardiff University
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583642 |