Aggrecan degradation in health and disease
The main aggrecan catabolite, found in samples of synovial fluid from patients with arthritis, and released from cartilage explant cultures exposed to IL-1, both have the amino-terminal amino acid sequence 374ARGSV ... (human sequence enumeration) corresponding to cleavage at the 'aggrecanase s...
| Main Author: | |
|---|---|
| Published: |
Cardiff University
2004
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583487 |