Identification and characterisation of a family of aspartic proteases in the apicomplexan parasite Toxoplasma gondii

Identification and characterisation of a family of aspartic proteases in the apicomplexan parasite Toxoplasma gondii

Parasites of the phylum Apicomplexa, including Toxoplasma gondii and Plasmodium falciparum, are major pathogens of man and domestic animals. Aspartic proteases play fundamental roles in eukaryotic biology, and have been validated as drug targets in several pathogens. The identification of the comple...

Full description

Bibliographic Details
Main Author:	Shea, Michael William
Published:	Imperial College London 2007
Subjects:	571.999
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582543

Similar Items

Use of molecular tools to investigate the prevalence and transmission routes of toxoplasma in woodmice and humans
by: Gerwash, Omar Mustafa
Published: (2007)

Characterisation of glutamate-gated chloride channels from Dirofilaria immitis
by: Yates, Darran Michael
Published: (2003)

Cryptosporidium parvum : host-parasite interactions
by: Pollok, Richard
Published: (2002)

The effects of gene flow on local adaptation in a natural host-parasite system
by: Webster, Lucy M. I.
Published: (2005)

Molecular epidemiology of Schistosoma japonicum
by: Shrivastava, Jaya
Published: (2005)

The impact of a shared microsporidian pathogen upon a Drosophila-parasitoid system
by: Futerman, Peter Harold
Published: (2005)

Changes in golden hamster behaviour and attractiveness to the sand fly Lutzomyia longilpalpis as a result of Leishmania infection
by: Nevatte, Tracy
Published: (2006)

Analysis of secreted proteins from the ectoparasitic nematode Xiphinema index
by: Furlanetto, Cleber
Published: (2004)

A bioinformatics and molecular analysis of antigenic variation in African trypanosomes
by: Marcello, Lucio
Published: (2006)

A mathematical modelling frame-work for immuno-epidemiology of Guinea worm infection
by: Netshikweta, Rendani
Published: (2016)

Studies of gene expression control in the apicomplexan parasite Toxoplasma gondii
by: Behnke, Michael Sean
Published: (2008)

Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
by: Pratt, Steven, et al.
Published: (2013)

Immunological studies on the related apicomplexan parasites toxoplasma gondii and plasmodium chabaudi AS
by: Couper, Kevin Nisbet
Published: (2003)

In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii.
by: Zhongqiang Chen, et al.
Published: (2008-01-01)

BASE EXCISION REPAIR APURINIC/APYRIMIDINIC ENDONUCLEASES IN APICOMPLEXAN PARASITE TOXOPLASMA GONDII
by: Onyango, David O.
Published: (2012)

Mutual interactions of the apicomplexan parasites Toxoplasma gondii and Eimeria tenella with cultured poultry macrophages
by: Runhui Zhang, et al.
Published: (2018-08-01)

Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii and anti-cancer molecules
by: Opsenica Dejan M., et al.
Published: (2015-01-01)

The Developing Relationship Between the Apicomplexan Toxoplasma Gondii and Schizophrenia with Emphasis on Parasitic Host Invasion
by: Mills, Hollie Mae
Published: (2013)

Checkpoints of apicomplexan cell division identified in Toxoplasma gondii.
by: Carmelo A Alvarez, et al.
Published: (2017-07-01)

Characterization of Rad51 from apicomplexan parasite Toxoplasma gondii: an implication for inefficient gene targeting.
by: Sita Swati Achanta, et al.
Published: (2012-01-01)

Self-mating in the definitive host potentiates clonal outbreaks of the apicomplexan parasites Sarcocystis neurona and Toxoplasma gondii.
by: Jered M Wendte, et al.
Published: (2010-12-01)

The crystal structure of zwitterionic 2-{[(4-iminiumyl- 3-methyl-1,4-dihydropyridin-1-yl)methyl]- carbamoyl}benzoate hemihydrate
by: C. S., Chidan Kumar, et al.
Published: (2017)

Three closely related (2E,200E)-3,300-(1,4-phenylene)- bis[1-(methoxyphenyl)prop-2-en-1-ones]: supramolecular assemblies in one dimension mediated by hydrogen bonding and C-Hp interactions
by: Aijia, Sim, et al.
Published: (2017)

Two closely related 2-(benzofuran-2-yl)-2-oxoethyl benzoates: structural differences and C 14H...O hydrogen-bonded supramolecular assemblies
by: Li, Yee Then, et al.
Published: (2017)

6-(Hex-5-enyloxy)naphthalene-2-carboxylic acid
by: Rahman, Md. Lutfor, et al.
Published: (2014)

6-Cyanonaphthalen-2-yl 4-hexylbenzoate
by: Rahman, Md. Lutfor, et al.
Published: (2014)

Crystal structure and Hirshfeld surface analysis of (2E,20E)-3,30-(1,4-phenylene)bis[1-(2,4-difluorophenyl) prop-2-en-1-one]
by: Huey, Chong Kwong, et al.
Published: (2017)

Crystal structure of (E)-4-{2-[4-(allyloxy)phenyl]- diazenyl}benzoic acid
by: Rahman, Md. Lutfor, et al.
Published: (2014)

Crystal structure of 3-{5-[3-(4-fluorophenyl)-1- isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2- one ethanol monosolvate
by: Rahman, Md. Lutfor, et al.
Published: (2016)

Crystal structure of 4-({(1E,2E)-3-[3-(4-fluorophenyl)- 1-isopropyl-1H-indol-2-yl]allylidene}amino)-1H- 1,2,4-triazole-5(4H)-thione
by: Kulkarni, Ajaykumar D., et al.
Published: (2015)

Crystal structure of 4-({(1E,2E)-3-[3-(4-fluorophenyl)- 1-isopropyl-1H-indol-2-yl]allylidene}amino)-5- methyl-1H-1,2,4-triazole-5(4H)-thione
by: Kulkarni, Ajaykumar D., et al.
Published: (2015)

mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway
by: Andréa Rodrigues Ávila, et al.
Published: (2018-01-01)

Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii.
by: Marc-Jan Gubbels, et al.
Published: (2008-02-01)

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy.
by: Adam James Reid, et al.
Published: (2012-01-01)

Structural insights into host cell adhesion by Toxoplasma gondii MIC4
by: Cowper, Ben
Published: (2012)

Toxoplasma gondii infection of rat retinal vascular endothelial cells
by: Brunton, Catriona Lindsay
Published: (2002)

An Overview of Peripheral Blood Mononuclear Cells as a Model for Immunological Research of Toxoplasma gondii and Other Apicomplexan Parasites
by: John Alejandro Acosta Davila, et al.
Published: (2019-02-01)

Elucidating the canonical and non-canonical functions of the autophagy protein TgATG8 in the apicomplexan parasite Toxoplasma gondii
by: Leveque, Maude
Published: (2016)

The use of molecular biological tools to investigate transmission routes and epidemiology of Toxoplasma gondii
by: Williams, Richard Huw
Published: (2005)

2,6-Diamino-4-(4-chlorophenyl)-1-methyl-1,4-dihydropyridine-3,5-dicarbonitrile
by: Purushothaman, Michael, et al.
Published: (2014)