Enzymatic activity of the four human glutathione S-transferase PI variants towards nitrosourea anticancer drugs

Glutathione S-transferases (GST) are a superfamily of detoxifying enzymes present in most life forms. They catalyse the conjugation of the tripeptide glutathione (GSH) to a wide variety of exogenous and endogenous compounds with electrophilic functional groups to form more soluble and non-toxic pept...

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Bibliographic Details
Main Author: Diogo Martins Vaz Haley, Ana Rita
Other Authors: Littlechild, Jennifer
Published: University of Exeter 2013
Subjects:
500
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579995