Modification of splicing patterns using artificial enhancer sequences within tripartite structure
Genes SMN1 and SNM2 encode SMN protein which is essential for motor neurone survival. In Spinal Muscular Atrophy patients, absence of functional SMN1 means functional SMN protein is encoded by SMN2 alone. SMN2 splicing products do not usually include exon 7, which is required for functional SMN prod...
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University of Leicester
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579202 |