Characterisation of transgenic mouse models of Alzheimer's disease

A number of transgenic mouse models have been developed to study the molecular and pathological alterations associated with Alzheimer’s disease (AD). The 3xTg mouse is widely used as a research tool and carries mutations in the amyloid precursor protein (Swedish APP K670N/M671L), presenilin 1 (PS1M1...

Full description

Bibliographic Details
Main Author: Graham, Lindsay
Other Authors: Sutherland, Calum ; Lambert, Jeremy
Published: University of Dundee 2011
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578828