Engineering polysialylation of scFvs and its effects on function

Antibody engineering for drug therapy has become a major industry in recent years, with much work focussed on the development of recombinant antibody fragments in therapeutic and diagnostic applications. An important consideration when engineering antibodies, especially rapidly clearing fragments is...

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Bibliographic Details
Main Author: Vyas, Bijal
Other Authors: Deonarain, Mahendra ; Mann, David ; Haslam, Stuart
Published: Imperial College London 2013
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576027