Targeting MAML for the inhibition of notch signalling, using Antp fusion proteins

The highly conserved Notch signalling pathway plays a major role in both metazoan development and adult tissue renewal. Deregulation of this pathway is linked to several diseases, including cancer. Various strategies for Notch signalling inhibition are now being investigated as promising new approac...

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Bibliographic Details
Main Author: Colucci, Silvia
Other Authors: Dallman, Maggie ; Byrne, Bernadette ; Deonarain, Mahendra
Published: Imperial College London 2013
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.574035