Organic solvent nanofiltration in the synthesis of DNA oligonucleotides and heterobifunctional polymers
DNA and RNA oligonucleotides are molecules of great interest due to their potential application as antisense and RNAi drugs. Currently, solid phase synthesis (SPS) is the method of choice for their synthesis due to its simplicity, automation, and simple intermediate purification. However, large scal...
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Imperial College London
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.574020 |