The role of CKS proteins in cancer development
The mammalian CKS family consists of two highly conserved proteins, CKS1 and CKS2. Both are able to bind to cyclin dependent kinases 1 and 2 (CDK1 and CDK2) with high affinity and were suggested to modulate CDK activity and thus cell cycle control. CKS proteins have also been reported to facilitate...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572259 |