Investigation of the role of inflammation in drug-induced hepatotoxicity
Drug-induced liver injury (DILI) is the most frequent cause for withdrawal of approved drugs and attrition of drug development. Although the cellular mechanisms of DILI leading to overt tissue and organ damage are still not fully defined, model hepatotoxins such as acetaminophen (paracetamol; AP AP)...
Main Author: | |
---|---|
Published: |
University of Liverpool
2011
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569176 |