Mechanotransduction of the Notch signalling pathway via the negative regulatory region
The Notch receptor is part of a highly conserved omnipresent developmental pathway that has crucial roles in developing and self-renewing tissues. During activation of the signalling pathway Notch binds to its ligand, presented on a neighbouring cell. It is thought that this results in a conformatio...
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University of Manchester
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568619 |