Ca2+ dependent activation of extracellular signal regulated kinases 1 and 2 : role of intrasynaptosomal Ca2+ stores

The aim of the thesis was to examine how Ca2+ activates the ERK pathway and the contribution of Ca2+ released from intracellular stores in physiological and pathophysiological conditions using isolated nerve terminals (synaptosomes) in a presynaptic model. The Ca2+-dependent phosphorylation/activati...

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Bibliographic Details
Main Author: Nizami, S.
Published: University College London (University of London) 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568242