The role of germline-encoded T cell receptor complementarity determining regions in T cell selection and function
αβ T cell Receptors (TCR) recognise peptide antigen (p) presented on Major Histocompatability Complexes (MHC) via Complementarity Determining Regions (CDRs). TCRs are required to respond to a vast plethora of differing antigens and the CDR regions are suitably diverse, encoded by an array of gene-se...
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Imperial College London
2013
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568026 |