Investigation into the role of novel interferon lambdas in the treatment of viral disease, primarily hepatitis C

Interferon lambdas (IFNλs), termed IFN-λ1, IFN-λ2 and IFN-λ3, or IL-29, IL-28A and IL-28B are a recently identified family of cytokines with antiviral activity. IL-28A/B and IL-29 bind to a novel heterodimeric receptor complex formed between IL-28 receptor (IL-28R) and IL-10 receptor (IL-10R2). Type...

Full description

Bibliographic Details
Main Author: Lowe, Rhiannon May
Other Authors: Thursz, Mark ; Morley, Peter
Published: Imperial College London 2012
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568015