In vitro systems to predict hepatotoxicity : models based on hepatocarcinoma cell lines
The liver has a major role in the metabolism of both endogenous and exogenous compounds. In drug development, reliable and reproducible results regarding the toxicity of a new compound must be obtained. The gold standard is freshly isolated primary human hepatocytes; however, these are costly, diffi...
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University of Newcastle Upon Tyne
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.566897 |