Regulation of renal brush-border glucose transport in response to metabolic dysregulation
Diabetic nephropathy is a consequence of hyperglycaemia-induced renal cell damage and a major contributor to end-stage renal disease in later stages of diabetes. Previous studies, in type I diabetes, observed PKC-βI-dependent GLUT2 recruitment to the proximal tubule brush-border membrane (BBM) as a...
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University College London (University of London)
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565314 |