Structural and energetic characterisation of interactions at the nucleotide-binding site of Hsp90
Heat Shock Protein 90 (Hsp90) is a ubiquitous molecular chaperone linked to the maturation and activation of a wide range of 'client proteins'. These include steroid hormone receptors, receptor tyrosine kinases and p53. Hsp90 activates ‘clients’ through a series of conformational changes d...
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University College London (University of London)
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565220 |