The role of polyhomeotic in polycomb group-mediated regulation of the tumour suppressor P16INK4A
The INK4A tumour suppressor gene is negatively regulated by the Polycomb Group (PcG) complexes, which plays an important role in stem cell- and cancer biology. Polycomb Repressive Complex 1 (PRC1) members posterior sex comb protein BMI1 and polycomb proteins CBX7 and CBX8 have been shown to be direc...
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University College London (University of London)
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564979 |