Transcription-coupled nucleotide excision repair and its regulation by the DNA damage checkpoint

Elaborate DNA repair mechanisms have evolved, allowing cells to repair damages in their genomes. Nucleotide excision repair (NER) removes a variety of helix-distorting lesions, including those caused by ultraviolet (UV) irradiation. NER operates via two subpathways. Transcription-coupled repair (TC-...

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Bibliographic Details
Main Author: Taschner, M. J.
Published: University College London (University of London) 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564756