Elucidating the role of α-synuclein on dopamine homeostasis using improved human dopaminergic cell models

Parkinson's disease (PD) is a devastating neurodegenerative disorder with cardinal motor symptoms linked to death of nigrostriatal dopaminergic neurons. Several findings place the protein cc-synuclein firmly at the centre of PD research. First, co-synuclein is the main component of Lewy bodies,...

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Bibliographic Details
Main Author: Lourenço Venda, Lara Patricia Mateus
Other Authors: Wade-Martins, Richard
Published: University of Oxford 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558331