Investigating the role of ERK in microtubule-interferin agent-induced cell survival and death
Activation of the mitotic checkpoint by microtubule-interfering drugs (MIAs) such as r- axol causes mammalian cells to undergo apoptosis. Previous studies have shown that tr atment with such drugs activate the extra-cellular regulated kinase (ERK) pathway, causing the cells to arrest in mitosis and...
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University of Leicester
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558096 |