Role of suppressor of cytokine signalling 1 and 3 in rhinovirus infection in vitro and in vivo

Rhinovirus (RV) infection is responsible for most asthma exacerbations. Defective RV induced interferon (IFN)-β and IFN-λs has been observed in asthmatic bronchial epithelial cells (BECs). Suppressors of cytokine signalling (SOCS) are negative regulators of cytokine signalling including IFNs. This s...

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Bibliographic Details
Main Author: Gielen, Vera
Other Authors: Johnston, Sebastian ; Edwards, Michael
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555942

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