Design and synthesis of novel lanthanide chelates for use in magnetic resonance imaging (MRI)

This thesis reports a series of novel Ln-DO3A based complexes, modulation of emission intensity (Eu and Tb) has been achieved and relaxivity, r1, (Gd) has been shown. Propargyl-appended lanthanide complexes derived from DO3A, has a hydration state, q = 2. They undergo Cu(I) catalysed cycloaddition r...

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Bibliographic Details
Main Author: Stasiuk, Graeme James
Other Authors: Lowe, Mark
Published: University of Leicester 2010
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551753