The role of canonical Wnt/GSK3ß/ß-catenin signalling in stem cell self-renewal and differentiation

Canonical Wnt signalling influences the 'sternness' of both embryonic stem (ES) cells and haemopoietic stem cells (RSC). In this study we investigated how modulation of the canonical Wnt pathway affected ES cell self-renewal and haemopoietic differentiation. We observed that Wnt activation...

Full description

Bibliographic Details
Main Author: Tarafdar, Anuradha
Published: University of Ulster 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551569