Functional properties and pharmacology of extrasynaptic GABA-A receptors

The “ambient” GABA that is present in the extracellular space surrounding all neurons of the brain is believed to be capable of persistently activating high‐affinity extrasynaptic GABA-A receptors to generate a tonic membrane conductance. This generates a form of shunting inhibition that is capable...

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Bibliographic Details
Main Author: McGee, Thomas Patrick
Other Authors: Hosie, Alastair ; Brickley, Stephen
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550236