Synthesis and properties of triplex-forming oligonucleotides containing 2'-modified nucleoside analogues
Triplex-forming oligonucleotides (TFOs) bind to the major groove of the DNA duplex via the Hoogsteen interactions to generate triple helices. Potential applications of triplex technology are in regulation of gene expression, site-directed gene-knockout, mutation correction and as tools in molecular...
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University of Southampton
2011
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548218 |